EasyJet expects a significant increase in corporate passengers following an agreement which gives Amadeus and Galileo more reliable access to its fares.
The move follows the development of new technology which will link the airline's system directly with the two GDSs.
The move could have wider implicatons, particularly if the technology is adoped by other low cost carriers.
Immediate access to frequent fare changes means TMCs will be able to book low cost seats with confidence that they will get the best deal on the flight requested.
This should end the embarrassment caused when a travel manager or individual business traveller finds a lower fare by accessing an airline's web site.
According to Jasper Soderstrom, head of Amadeus's low cost carrier unit, this happens "often enough to be annoying".
A survey in Scandinavia showed it occurred on average once in every ten bookings.
EasyJet will charge an administration fee of EUR7.50 for one sector, EUR6 for each of two two or EUR5 per flights if the transaction involves multiple sectors.
Later this month Amadeus, which has been piloting the scheme in Germany, France, Spain and UK, will extend the technology to agents worldwide.
Galileo will do likewise in the UK by the end of December and across the rest of Europe early next year.
Aimed at business rather than leisure travel agents, the technology will also be available to other low cost carriers.
Bryan Conway, Galileo's managing director for Europe, the Middle East and Africa, says: "Low cost airlines account for 36% of European short haul traffic but only 1% of GDS bookings.
"Clearly we expect the volume to increase. We would expect others who have discounted the GDSs to follow easyJet's example.
"We realise that we have got to stop trying to force airlines to adapt to a classic GDS template and adjust our requirements to theirs."
Currently about 20% of easyJet's passengers are business travellers. Chief executive Andy Harrison said "fundamental changes" are taking place in the short haul market.
With easyJet taking over former British Airways franchise operator GB Airways and opening new bases at primary airports, he said "it makes sense to make our product available to people who would previously flown with legacy carriers."
By Roger Bray