Virgin Atlantic is cutting 500 jobs as it looks to restructure areas of the business and trim costs.
The announcement comes just months after the airline announced a return to profitability.
Virgin Atlantic said the aim was to create a simpler, more efficient structure with few management layers.
In March the airline made £14.4 million in 2014, representing an improvement of £65.4 million on the previous year.
In a statement it said: "Virgin Atlantic will build on its successful return to profitability by structuring the business in a simpler, more efficient way with fewer management layers, bringing the entire business closer to the customer.
"To achieve this, Virgin Atlantic is planning a reduction of approximately 500 support and managerial roles, which will be achieved through a combination of natural attrition, redeployment and redundancies.
"This programme will be handled in a way that provides the best possible support to all those that are impacted. These changes will take place over the next few months, with a target of completing the programme by the end of the year.
"Virgin Atlantic is aiming to reduce its non-fuel costs through focusing on driving efficiency and simplicity throughout all areas of the business whilst delivering an even better customer experience.
Chief executive, Craig Kreeger, added: "As a people oriented business, these are extremely tough decisions to take, but we know they are necessary to secure our future.
"We are committed to supporting our people as we deliver against these plans."