Expedia Corporate Travel (ECT), an online agency, has changed its name to Egencia.
The newly named company will remain a part of the wider Expedia Inc group.
Egencia said the reason for the changes was that it had become a "strong, growing global business on a scale that warrants its own distinct brand."
Jean-Pierre Remy, president of Egencia, said: "The Egencia brand reflects who we truly are as a company.
"Having led innovation in the corporate travel industry, we see this as an opportunity to further define ourselves in the marketplace and set a foundation for further advancements in the years to come."
Dara Khosrowshahi, Expedia Inc's ceo, was quoted in the London Financial Times as saying: "The goal is really to set this brand as an industry heavyweight to compete directly with Amex and Carlson Wagonlit Travel.
"We are going to expand Egencia on a global basis.
"This might not seem like a time to invest in a new brand. But with Egencia, corporations are looking for ways of saving on their corporate travel spend."
He added that the move into a separate brand was recognition that the corporate travel business had proved itself.
ECT was founded in 2002 and is based in Seattle.
Its new name, Egencia comes from a Paris-based agency it took over in 2004.
It said it was now the fifth largest travel management company in the world and was
introducing new tools for business travellers, travel managers and travel bookers that "truly transform the business of travel."
Austrian issues writ over absent investment
Austrian Airlines has filed a lawsuit over its dispute with Sheikh Al Jaber about a 150m investment in the carrier.
In a statement Austrian said it was a "necessary step to safeguard legal deadlines."
It said it had done "everything within its power to reach a solution by way of negotiation" with Mr Al Jaber.
It said he had "not so far been prepared to discuss any solution other than termination of the contract subject to mutual waiver of claims."
In a deal announced between Mr Al Jaber and the airline, he was to invest 150m in return for a 20% stake.
According to Austrian, Mr Al Jaber later indicated that the deal was off.
The airline said that its initial research to identify a possible strategic partner had produced "more options than expected."
It said its next step was further research to see what which strategic models would be the best fit for the airline.
It said it had also identified "some two dozen starting points" for its optimisation programme, a cost cutting measure spurred by rising fuel prices.